A teenage genius deals with the usual problems of growing up, on top of being a licensed physician in a difficult residency program.
Cast:Neil Patrick Harris , Max Casella , Belinda Montgomery , Lawrence Pressman , Kathryn Layng , James Sikking , Markus Redmond , Lucy Boryer , Mitchell Anderson , Lisa Dean Ryan , Rif Hutton , Robyn Lively , Lainey Hashorva , Linda Klein , Carlease Burke , James Hong , Huck Liggett , Sami Chester
April 29, 1992. Doogie, Vinnie and the hospital staff deal with the aftermath of the L.A. Riots.
Doogie dates Katherine's new boss. David's angioplasty patient needs to consider putting her mentally-challenged, adult daughter into a group facility.
After Doogie lets a burglar into the house, he considers buying a gun.
When Doogie decides to get his own place, he and his parents go look at some apartments but none of them is to his liking. But when he finds a loft, he feels this is it but his father refuses to support him if he decides to take it.
Doogie has to learn how it feels to be a patient. So he is admitted, given some props to simulate elder difficulties, and is subjected to the same treatment and experiences as his patients.
Doogie makes a mistake during a surgery and starts to doubt himself. Vinnie agonizes over the presidential election.
Doogie dates a deaf patient and wants to "fix" her. Vinnie tries to raise money to make his movie.
Vinnie snakes a girl from Doogie which bruises Doogie's ego causing him to act obnoxiously. Ray passes the EMT test and starts second guessing himself.
Doogie battles his conscious over whether or not to report a heart transplant candidate's poor behavior. Janine returns wanting Vinnie back.
Doogie and his father disagree on whether a child is a victim of child abuse. Doogie and Vinnie try video dating.
David throws out his back, and Katherine takes his place on the father-son fishing trip not to the initial delight of Doogie. Vinnie "nurses" the ailing Howser back to health.
Doogie is planning his New Year's celebration. He comes home and finds a girl there. He learns that the man who rented him his place also rented it out to her. They try to live together but the girl is very fancy free which drives the uptight Doogie crazy.
Doogie's locker room talk embarrasses the nurse he's dating causing her to get even. Vinnie unknowingly moves into a dorm room with a gay man.
Vinnie is upset when his not yet divorced father starts dating another woman. David is offered the position of Head of Family Medicine at the hospital.
Nurse Faber has a date with someone else causing Doogie to deal with his hurt feelings by imagining a Sherlock Holmes scenario. Curly gets engaged.
After Vinnie loses his virginity to Laura, he feels not good enough for her and begins to behave erratically. Doogie treats a famous actress for a mysterious illness.
Doogie learns that his former babysitter and crush, Rachel Wilson is in town. He hasn't seen her since he was 10 years old. Could his old fantasies finally come true? Vinnie attempts to get his movie script to a famous Hollywood actor, Nathan Gage.
A young patient at the hospital develops a crush on Doogie. A computer glitch in Vinnie's bank account gives him $16,000.
Doogie becomes enraged when a newspaper cartoonist, also a patient at the hospital, uses him as a caricature in his comic strip.
Vinnie serves on a jury and angers the other jurors by casting the only dissenting vote. Doogie finds out that a well-respected doctor has never gotten his medical license.
Doogie, feeling unsatisfied with his position in life, decides to take acting lessons. This develops into a real identity crisis, so Doogie decides to leave the hospital and travel the world to find himself.