Hamilton's Pharmacopeia

Join an incredible journey through the history, chemistry and societal impacts of the world's most extraordinary drugs.

Cast:Hamilton Morris , Jason Wallach , Timothy Wyllie , Steve-O , Erik Hoffstad , Christ Bearer , Ann Shulgin , David E. Smith , Frank Lyga , MarÃa Sabina , Jean Luc Mazeau , Filogonio Garcia , Jenny Wild , Etienne Van Zyl , Rico Jocelyn Mazeua , Colin Foord , Laura Guzman , Darrell Lemaire

1Season 1

S1.E1 ∙ The Story of the South African Quaalude

Tue, Sep 27, 2016

South Africa is the last place on earth Quaaludes can still be found. Hamilton travels there to study the drug and finds a dark history of medical experimentation.

2Season 1

S1.E2 ∙ A Positive PCP Story

Tue, Sep 20, 2016

Hamilton travels across the USA meeting with addicts, dealers, chemists, and celebrities to trace the history of PCP from its pharmaceutical origins to its escape onto the streets.

3Season 1

S1.E3 ∙ Shepherdess: The Story of Salvia Divinorium

Wed, Nov 9, 2016

From the heavenly cloud forests of Oaxaca to a viral video of Miley Cyrus, Hamilton investigates the inconspicuous yet extraordinary psychedelic plant Salvia divinorum.

4Season 1

S1.E4 ∙ Magic Mushrooms in Mexico

Wed, Nov 16, 2016

From the Aztec empire to the underground laboratory, Hamilton explores magic mushrooms with the help of shamans, clandestine growers, and ethnomycologists.

5Season 1

S1.E5 ∙ Fish N' Trips

Wed, Nov 30, 2016

Hamilton embarks on an aquatic adventure to Reunion Island and Madagascar to investigate ichthyoallyeinotoxism and a twisted history of hallucinogenic fish.

6Season 1

S1.E6 ∙ The Lazy Lizard School of Hedonism

Wed, Dec 7, 2016

In our last episode, we meet with famed LSD chemist Casey Hardison in the Nevada desert and embark on a road trip to visit an unsung hero of psychedelic history - Darrell Lemaire.

1Season 2

S2.E1 ∙ The Psychedelic Toad

Tue, Nov 28, 2017

Hamilton embarks on a quest to answer the most important question in ethnoherpetological history and along the way, he finds the power of love.

2Season 2

S2.E2 ∙ Peyote: The Divine Messenger

Tue, Dec 5, 2017

From the greenhouses of Thai cactophiles to the Tamaulipan thornscrub, Hamilton traces the history of peyote with the help of a Native American peyotist.

3Season 2

S2.E3 ∙ Kratom: The Forbidden Leaf

Tue, Dec 19, 2017

Hamilton investigates the pharmacology and traditional uses of Kratom, a Thai tree with opioid-containing leaves.

4Season 2

S2.E4 ∙ Wizards of DMT

Tue, Dec 12, 2017

Hamilton travels across North America to study how and why DMT exists in the environment and the laboratory.

5Season 2

S2.E5 ∙ Ketamine; Realms and Realities

Tue, Dec 26, 2017

Hamilton heads to India to see industrial Ketamine synthesis, and speak with therapists and luminaries in an attempt to understand the role of dissociative anesthetics in society.

6Season 2

S2.E6 ∙ A Clandestine Chemist's Tale

Tue, Jan 2, 2018

Hamilton meets an unsung hero of the psychedelic underground and hears a tragic tale of MDMA synthesis and chemiluminescence.

7Season 2

S2.E7 ∙ A Fungal Fairy Tale

Tue, Jan 9, 2018

Hamilton ascends the Carpathian Mountains, microscope in hand, to learn how Europeans use Amanita muscaria, and uncovers the chemistry behind a mushroom-inspired pharmaceutical.

8Season 2

S2.E8 ∙ The Cactus Apprentice

Tue, Jan 16, 2018

Deep in the Andean highlands of Peru, Hamilton becomes the apprentice of a local shaman, learning how to use the night-blooming San Pedro cactus as a medicine.

1Season 3

S3.E1 ∙ Synthetic Toad Venom Machine

Mon, Jan 4, 2021

Haunted by past mistakes, Hamilton embarks on a journey to correct an error in his reporting and identifies the origin of an international toad venom smoking phenomenon.

2Season 3

S3.E2 ∙ A Positive Methamphetamine Story

Mon, Jan 11, 2021

Hamilton explores the simultaneous chemically seductive and insidiously dangerous world of crystal methamphetamine. A drug that has by rule of economics become one of the world's most popular ones.

3Season 3

S3.E3 ∙ Xenon: The Perfect Anesthetic?

Mon, Jan 18, 2021

Add a plot

4Season 3

S3.E4 ∙ Synethetic Ibogaine-Natural Tramadol

Mon, Jan 25, 2021

Hamilton travels to meet with several research scientists to understand how or why tramadol, believed to be a purely synthetic lab created substance, was found in harvested African ibogaine root. Is it also found naturally and we were previously unaware of it? Is there a different conclusion such as lab error or environmental waste contamination of the ibogaine root prior to its harvest? He then travels to Africa to learn how this plant is being used as a treatment for Tramadol addiction and a variety of other physical and mental ailments.

5Season 3

S3.E5 ∙ Bufotenine: In Search of Hataj

Mon, Feb 1, 2021

Succumbing to viewer requests, Hamilton journeys to South America to understand the legend of Bufotenine, the world's oldest psychedelic.

6Season 3

S3.E6 ∙ Ultra LSD

Mon, Feb 8, 2021

With the precise structure of LSD's molecular target identified, Hamilton discusses a new era of psychedelic research and, along the way, meets pioneers of the field.