After being shot in the line of duty, Harry Orwell was forced to retire from the San Diego Police Department. To supplement his police pension, Harry runs a private detective agency out of his beach house.
Cast:David Janssen , Anthony Zerbe , Paul Tulley , Henry Darrow , Farrah Fawcett , Les Lannom , Margaret Avery , Tom Atkins , Bill Henderson , David Moses , Richard Stahl , G.W. Bailey , Joanna Pettet , Kathleen Lloyd , Mel Stewart , Hal Williams , Julio Medina , Lou Frizzell
Lt. Trench is under investigation by Internal Affairs, suspected of killing an informant.
Harry is hired by a woman who can't remember whether she was responsible for a hit-and-run that gravely injured a teenager.
After Sue is kidnapped by diamond smugglers, Harry works hard to come up with their ransom demands.
Harry is hired by a wealthy woman to investigate the arrest of her housekeeper for murder. The investigation leads Orwell into a world of blackmail, hidden family secrets and murder.
Harry is hired to find out if a mentally challenged 19-year-old is involved when a woman is found strangled to death under the Santa Monica Pier.
On the trail of a missing woman, Harry finds himself investigating the leader of a religious cult and his chief disciple.
Harry reads in the paper that his old Korean War buddy died in a plane crash. His widow tells Harry about him acting strangely before his fatal flight and Harry decides to find out what really happened.
Spence, Harry's auto mechanic, fears his father is being mistreated at the 'old folks home'. When Spence's father dies, he hires Harry to investigate the Doctor at the home.
The victim of an elaborate frame, Harry is arrested for murder. While awaiting trial, Harry escapes and tracks down the real killer as he attempts to clear his name.
When members of a therapy group turn up murdered, the group psychiatrist suspects one of the members and hires Harry to investigate.
Harry is reunited with his ex-wife over a case of blackmail and murder. Through flashbacks, we see Harry and Elizabeth fall in love before breaking up over his spending too many hours on the job.
Harry is hired to find a drug-addicted, pregnant teenage girl who ran away from her policeman father. In the midst of this case, an old girlfriend comes back into Harry's life.
An old policeman friend dies from a suspected suicide but Harry doesn't believe it. His investigation leads him to an 8-year-old murder case involving the family of a wealthy industrialist.
A young lady is arrested for passing counterfeit money and she calls her classmate Lester for help. Lester in turn enlists Harry's help and soon they discover that her grandfather had been printing fake money. But now he's been kidnapped.
A woman who runs a gambling club is murdered and a book of hers that's filled with incriminating photos of influential people is stolen. Harry is hired to find and destroy that book and to protect a young woman who witnessed the murder.
An ex-con gets out of prison and looks up his old girlfriend, intent on getting his hands on his old suitcase, which he says contains $300,000. Harry is hired to find the suitcase, as well as to protect the woman in the middle of it all.
When a robbery goes awry, a standoff with the police ensues and Lt. Trench offers himself as trade for one of the hostages. Harry must find the thief's girlfriend before hostages are killed.
Answering an old friend's plea for help, Harry arrives at the meeting and soon finds out that his friend has been killed. Harry digs into the circumstances and discovers a tangled web of smuggling, threats, and murder.
A rape victim is turned away by the police who decline to prosecute. She turns to Harry for help finding justice.
Harry goes undercover to infiltrate a ring of car thieves and drug traffickers.
The fourth "Lester" episode is a pilot for what would have been a spin off "Fong and Hodges" series. (Sadly, the episode's relatively low ratings may have been the tipping point in ABC deciding to cancel "Harry O." Harry receives a note from Simon Applequist, asking Harry to come to a meeting at Applequist's palatial mansion. Applequist is a fabulously successful businessman who made more enemies than even he could count. Applequist greats Harry and introduces him to his various relatives -- one of whom is Lester Hodges. Then he fixes a baleful glare on the group and announces someone has sent him a threatening audiotape. Applequist puts the tape on and sits back as a whispered death threat plays. As the voice hisses: "Wait to die! Wait to die!" that's what Applequist does. Officially he suffered a heart attack, but Lester and his oft-mentioned mentor, Dr. Creighton Fong find that Applequist was poisoned by a venom found in the skin of an Amazon River basin alligator. At the reading of the will, Applequist's attorney reveals that Applequist has left almost everything to his brother-in-law Edward Tabor. Lester pokes around and gets everyone to whisper the same word to him, which he records. Dr. Fong finds that the word was uttered by Tabor. Lester goes to Tabor and confronts him, seeing his lab of various exotic poisons. Sure enough, Tabor has a nearly-empty vial of caimanol, the poison, in his collection. But the moment Lester points this out to Tabor, who is sipping a drink, Tabor drops dead in his tracks -- the caimanol was planted in the drink. As Harry (who is off screen for most of this episode) leaves to check out the backgrounds of the suspects, one heir after another gets a lethal dose of caimanol in various fashions, until only two suspects are left. And Lester is one of them.
A young widow has a malpractice suit against the doctor who was treating her deceased husband, but after she is threatened by two men to drop the suit, her mother hires Harry to look into the Dr.'s past. Dead bodies begin piling up around Orwell, including Spence, his auto mechanic. The investigation leads Harry into the world of organized crime, hit-men and the safe-deposit box of the deceased husband.