Young Punky Brewster is abandoned with her dog, Brandon, in a supermarket. When she befriends Henry Warnimont, her new family life begins.
Cast:Soleil Moon Frye , George Gaynes , Cherie Johnson , Sandy , Shanin Lonsway , Susie Garrett , Ami Foster , Casey Ellison , T.K. Carter , Eddie Deezen , Timothy Stack , Dody Goodman , Allyn Ann McLerie , David Ruprecht , Loyita Chapel , Carl Steven , Brent Chalem , Andy Gibb
Penelope "Punky" Brewster is an abandoned 8-year-old who wanders into an empty apartment in Chicago. The manager of the building is a 60-year-old curmudgeon named Henry Warnimont, who begrudgingly agrees to let her sleep on his couch until more suitable arrangements can be made.
Henry fails to stop a social worker from putting Punky in an orphanage.
In the first segment, Punky and her friends convert Henry's study room into her bedroom without asking him first. In the second segment, Henry takes Punky shopping and she wanders off.
In the first segment, Henry, Punky's foster father, takes over the task of walking her and her hyperactive friends Cherie, Margeaux, Scotty and Allen to school after Mrs. Johnson, Cherie's grandmother, challenges him to the job. In the second segment, Henry turns Punky onto the sport of fishing when she complains of being bored.
As the Chicago Cubs play in their first post-season championship since 1945, proud Cubs fan Henry tries to get tickets for Punky and himself.
As the school's parent-teacher night approaches, Punky is upset by Margaux's insensitive comments about foster parents and foster children.
In the first segment, Henry gives Punky a lucky nickel to keep with her while she goes for a booster shot. In the second segment, Punky can't sleep, so Henry agrees to let her stay up and watch the opera with him on TV.
Punky, Cherie, and Margaux compete in a beauty pageant hosted by pop singer Andy Gibb.
Punky and Cherie start a dog grooming business so that they can help make ends meet in their respective homes.
Henry throws out Punky's worn-out old doll after the children's attempt to repair it fails. This upsets Punky, so Henry searches throughout the city to find it.
Christmas is approaching, and the only thing Punky wants is to find her mother.
By playing Santa at school and saying he can do anything if she believes in him hard enough, Henry has inadvertently convinced Punky that Santa Claus will bring back her mother. Now he must find the woman, but the search is fruitless until an antiques dealer provides a possible clue.
Punky helps her piano teacher get into the music business.
Henry is reunited with a woman he planned to marry in 1941; when Pearl Harbor was attacked, he enlisted in the Merchant Marines and did not see her again until now.
Punky runs away when he learns that when Henry and Maggie are to be married, she'll be sent to boarding school in Europe.
After getting in trouble for slugging a boy at school, Punky dreams of life 80 years into the future where everyone has found love except for her.
Henry scolds Brandon for eating several valuable stamps. After that, Punky takes him on a walk, where he is hit by a car. He is rushed to the veterinary hospital, where his prognosis is grim.
Henry purchases a video camera for his photo studio and firmly warns Punky that she is not to touch it under any circumstances. However, while he's away, she and her friends make an exercise tape and think he won't know it - until the camera breaks.
Punky, Cherie, and Margaux all want a highly sought-after doll, but Henry can only find one of them at the toy store.
Punky catches a boy breaking into her room and stealing from her. Henry takes the boy to Fenster Hall where Mike Fulton, one of the workers there, tries to bond with him.
T.C.'s criminal mentor, Blade, sends him back to Fenster Hall to steal the money from the upcoming benefit auction.