Follows the lives and loves of four close, but very different, sisters of the Reed family living in Winnetka, Illinois.
Genre: Drama
Cast:Swoosie Kurtz , Patricia Kalember , Sela Ward , Elizabeth Hoffman , Garrett M. Brown , Julianne Phillips , Heather McAdam , Jill Novick , Sharon Martin , Ed Marinaro , Riff Regan , Dustin Berkovitz , Ryan Francis , Tasia Schutt , Ashley Judd , Sheila Kelley , Robert Klein , Nora Dunn
During a late-summer heat wave, Alex wants to have the perfect wedding for her mother and Judge Trueman Ventner. But Beatrice doesn't like her daughter's plans. While Alex spends a romantic evening with her ex-husband, Wade, Reed informs them that she wants to quit college to be with her boyfriend Kirby. Later, Reed informs everyone that she has married Kirby, and Alex reacts by breaking EVERY piece of crystal in her house. Meanwhile, Frankie is concerned that Georgie, who is seven months pregnant, may be over-exerting herself, so she hires a housekeeper for Georgie. While Cat prepares to leave town for college, Teddy fears that Beatrice will move away from everyone after she marries Truman.
Teddy finds a way to help her struggling clothing business when, after Alex invites her to a dinner party, Teddy meets Simon Bolt, a wealthy but cynical British corporate magnate who becomes interested in her work and wants to invest $10 million to help expand her business. Meanwhile, Laura, a sexy TV reporter, wants to know about Mitch and his fish store which makes Frankie jealous. Also, the very pregnant Georgie fights her sudden craving for chocolate.
Frankie decides to convert and raise a Jewish family with Mitch, much to the shock of the family, especially the conservative Beatrice. Meanwhile, Teddy and Simon fight over how to run Teddy's new clothing factory and over McKinley working for the company. Also, Alex helps Reed and Kirby with moving into their new apartment and afterward takes them into her house after they are evicted.
Georgie flashes back after learning John's plane crashed; Bolt coaches Teddy for a news conference spotlighting her line.
Teddy becomes concerned when she catches Cat drunk, Alex gets a lesson in political correctness, and Frankie fears she might be pregnant.
Alex thinks she accidentally killed a man, Frankie and Mitch spend the night in a haunted house, and Teddy learns of the secret that haunts Simon.
Mitch gets into a dispute with a friend who takes a fall outside of Mitch's Store, and Beatrice, Georgie and Alex win the lottery.
After being hit by a drunk driver, Georgie now trapped inside her car, goes into labor-while her sisters look on helplessly
Teddy has her first Fashion Show, and Georgie struggles with postpartum depression and her feelings toward Frankie and their shared child.
Alex proposes a line of Jewelry to Simon, Frankie and Beatrice feud over the upbringing of Frankie's baby, and Reed is caught in a test of wills between her father and Kirby.
Teddy learns that her high school beau has Aids, Alex enrolls in a writing class taught by a famous author and Frankie drives Georgie's family crazy.
During Frankie's first Hanukkah, a swastika is painted on Mitch's storefront, and John's dad shows up to make peace.
Restless Frankie wants to curtail her maternity leave, putting her at odds with Mitch; Teddy cautiously agrees to live with Bolt.
Teddy declares war on a fashion critic (Concetta Tomei); Georgie backs over a neighbor's (George Furth) chihuahua.
A screenwriter profiles Georgie's surrogacy and starts family fights; Alex tries to get her daughter and son-in-law to leave.
A fired employee takes Teddy hostage, but Bolt offers himself in exchange; Wade tells Alex he is remarrying.
A TV movie on the sisters unites Alex with her romantic idol (Patrick Duffy); guests Suzanne Somers, John Schneider.
As Alex undergoes breast-augmentation surgery, a small malignancy is found, forcing the removal of the tumor and part of her breast.
Worry over chemotherapy makes Alex more sarcastic; Teddy offers to sell her shares to ward off a takeover; tests indicate Evan is a genius.
Georgie is hired to write an advice column for the local newspaper; John thinks Teddy has fallen in love with him; Alex and Frankie accuse Truman of cheating on their mother.
A podiatrist (John Schuck) romances Alex; Frankie spends time with an executive; Georgie and John try to rekindle romance.
Bolt proposes to Teddy; Alex buys a wig from a mystic who claims it has powers; Frankie and Mitch consult a marriage counselor.
Moving into a new house makes Mitch confront Frankie; a diminutive Texas billionaire (Henry Gibson) buys out Teddy's firm.
The siblings fight as the airing of their TV movie approaches; Frankie takes a job offer in New York.