Newspaper illustrator John Moore meets with criminal psychologist (alienist) Dr. Laszlo Kreizler to investigate a serial killer in New York during the late 19th century.
Cast:Daniel Brühl , Dakota Fanning , Luke Evans , Robert Wisdom , Douglas Smith , Matthew Shear , Ted Levine , Martin McCreadie , Brian Geraghty , Q'orianka Kilcher , Matt Lintz , David Wilmot , Brittany Marie Batchelder , Rosy McEwen , Melanie Field , Emily Barber , Georgia Lowe , Matt Letscher
One year after The Alienist, with Sara Howard, now a private detective, seeking out Dr Kreizler's help in finding the kidnapped infant daughter of a visiting Spanish dignitary. Dr Kreizler reunites with Sara, John Moore and the rest of the original team, with their search for the missing child bringing them into contact with a mysterious woman with a murderous past who is connected to a notorious gang.
Sara uncovers a clue at the Siegel-Cooper department store that leads her into dangerous territory. Moore struggles to balance his personal and professional life as he investigates a link to New York's criminal underworld. Kreizler suspects dark goings-on at the Lying-In Hospital while former police chief Thomas Byrnes plots against their investigations.
Sara persuades a young nurse to disclose what happens behind closed doors. Meanwhile, Kreizler is convinced that hypnosis might unlock the traumatic memories of Señora Linares, and Moore introduces Sara to a well-connected friend to further the investigation.
The clock is ticking for the team to locate baby Ana. Meanwhile, Sara is worried about her young undercover detective Bitsy Sussman, and William Randolph Hearst hosts a lavish ball celebrating his goddaughter Violet's engagement to Moore.
The team is racing to find the killer responsible for murdering an employee at the Lying-In Hospital.
Sara and John continue to search for information about Libby. Kreizler is nearly ruined by a tragic accident. Sara and the team have to work with Thomas Byrnes to find a new missing child.
Sara, Kreizler, and Moore travel to Brooklyn in search of clues hidden in the killer's dark past.
Sara, Moore, and Kreizler struggle with decisions about their future paths.