Made from sugar, spice, everything nice and Chemical X by the Professor; Blossom, Bubbles, and Buttercup now use their superpowers and super cuteness to save the world (or at least Townsville) from evil villains and all things icky.
Genre: Animation, Action, Comedy
Cast:Amanda Leighton , Natalie Palamides , Kristen Li , Tom Kane , Tom Kenny , Roger Jackson , Roger Craig Smith , Jennifer Hale , Haley Mancini , Eric Bauza , Fred Tatasciore , Maurice LaMarche , Jake Goldman , Dee Bradley Baker , Jason Spisak , Jason Kaye , Lily Vonnegut , Cindy Robinson
After Mojo Jojo's latest creation threatens to blast him into tiny bits, the Powerpuff Girls are forced to take Mojo in.
When the Fashionistas unveil their new mind controlling perfume, The Powerpuff Girls must find a way to stop them before Townsville falls under their spell.
After being blasted by Duplikate, Blossom turns into a triple threat.
In an effort to make himself "great," Mojo steals the powers that makes the each of the Powerpuff Girls the heroes they are.
When Morbucks realizes that The Powerpuff Girls see her as a villain and not a friend, she sets out to turn the town against them.
When Morbucks falls in love, she finds the first thing money can't buy.
When a mysterious rain cloud plagues Townsville, Bubbles learns things aren't what they seem.
When an ancient prophecy spells doom for Townsville, the girls must race to stop it.
The Powerpuff Girls compete in a race against some of their most vicious villains, to win whatever is in the Mayor's "Mysterious Box Of Mystery."
After they get accused of a crime they didn't commit, The Powerpuff Girls and The Derbytantes have to find a way to clear their name!
After a chemical spill, the girls and Mojo find themselves trapped together.
Buttercup must go it alone to save her family from a kidnapping.
When the professor is kidnapped, the girls must go to a mysterious island to save him.
The Powerpuff Girls are sent to the arctic on a dangerous mission to find the key to saving the day.
On Halloween Night, Morbucks summons a monster that she didn't expect. And the Powerpuff girls now as withes must to a stop to it.
The girls must replace the Professor's Christmas present on Christmas Eve.
Buttercup is not a fan of Bubbles' newly created digital assistant.
When a mysterious new ice cream flavor takes Townsville by storm, the girls suspect there might be foul play.
When Bliss brings a new tech product to town, it's more powerful than imagined.
A new villain arrives in Townsville and gives the old villains an enticing offer.
When Buttercup loses the Professor's latest invention, she'll have to beat The Gangreen Gang at their own game to get it back.
The Professor makes new friends, but they may be the wrong crowd.
Bubbles and Buttercup make a deal without realizing the consequences.
The school play goes off the rails when the drama teacher interferes.
The Powerpuff Girls are tasked with keeping a priceless gem safe from thieves.
With Man-Boy on the loose, Donny must be prepared for anything.
When Princess Morbucks steals Octi, Bubbles' reaction surprises everyone, even her sisters.
When the Girls start playing soccer, the Professor goes overboard.