A group of doctors at Chastain Memorial Hospital face personal and professional challenges on a daily basis.
Genre: Drama
Cast:Matt Czuchry , Manish Dayal , Bruce Greenwood , Malcolm-Jamal Warner , Tasso Feldman , Emily VanCamp , Jane Leeves , Denitra Isler , Jessica Miesel , Shaunette Renée Wilson , Vince Foster , Jessica Lucas , Anuja Joshi , Michael Hogan , Morris Chestnut , Andrew McCarthy , Glenn Morshower , Kaley Ronayne
A cyberattack sends the hospital into a tailspin and Kit has to decide whether to pay the ransom. Conrad has to balance work with being a new dad. Devon and Leela debate where their relationship is going.
When Devon is found unconscious on the roof, the staff frantically retrace his steps to determine what happened. Billie fights with her son over a drug overdose. Bell helps Kit vet a new neurosurgeon.
An accident brings a familiar patient into the ER, the doctors must face the reality of how to proceed with the best care while questioning every decision. The Raptor and Leela treat a patient dealing the long-term effects of COVID
In trying to find a way to channel his emotions, Conrad puts all his effort in looking for answers. Raptor has a run-in with the police that ends up taking a surprising turn. Meanwhile, Leela begins noticing problems with a surgeon who has been Bell's mentor.
While looking for a distraction on Halloween, Conrad treats a group of witches who send the ER into chaos. Also, Devon treats a patient who thinks he is being haunted by ghosts. Meanwhile, on the way back from his vacation, Bell picks up a hitchhiker who is not what he seems to be.
Conrad brings a patient into the hospital who causes a high security crisis. An MMA brawl sends a well-known fighter to Chastain and all hands are on deck. Meanwhile, Bell and Raptor vie for the same position at the hospital, and Leela gets a visit from her sister.
A new group of interns start their first day with Devon at Chastain. Kit and Bell try to convince Conrad to come back to Chastain. The Raptor's mother ends up back in the ER. Leela and Padma deal with an unexpected visit from their parents.
Kit hires a surgical coach to watch over Bell and Raptor and help them brush up on their skills. Upon receiving attention from multiple women at the hospital, Conrad contemplates jumping back into the dating scene. Devon works with an elderly couple.
Conrad mentors Trevor whether to treat a patient whose luck seems to have run out.
When the first day of Kit's experimental Flight Go team programme sends Conrad out into the field, he builds a new relationship with a fellow doctor along for the ride; Devon works with Trevor on a patient with a mysterious fever.
A case turns personal for Conrad when the donor-recipient of Nic's heart is admitted to the emergency room; Bell is faced with a devastating diagnosis that causes him to make a heartbreaking decision.
Conrad and Cade examine a child showing signs of abuse. Devon and Leela encounter a woman having trouble breathing. Meanwhile, Bell eyes an open seat on the State Medical Board and Billie decides it's time to confront her past.
A tragic accident occurs at Jessica's sister's gender reveal party. Conrad, Irving and Trevor work on an influencer whose life is in danger due to a risky cosmetic procedure.
When Billie's past mistakes are exposed, the team struggles to find a way to support her. The nursing shortage hits Chastain. A simple cleaning job goes horribly awry.
As his clinical trial begins, Devon treats his first patient with a revolutionary medical fluid that doesn't go as planned. Meanwhile, an overdosed John Doe is rushed to Chastain, leading Conrad straight into a much bigger scandal than he expected. Then, a shocking secret regarding Cade's past is discovered.
Conrad and The Raptor help out an old friend whose heart problems reveal a bigger issue than they anticipated. Bell confronts the Medical Board about the cases he's been investigating.
Conrad treats one of Gigi's classmates whose stomach ache turns much more serious. Devon takes several interns to the senior living facility. Leela uncovers unsettling news.
When Conrad confronts a pharmacy owner about fraudulent prescriptions, she turns up dead. The ER is sent in to chaos when both families on the end of a street racing accident are present.
With AJ on leave to take care of his mother, the hospital scrambles to organize without him. A camping trip leaves a patient with a fatal disease no one can diagnose.
Conrad and Cade work with a Medicare patient who sheds some light of prescription fraud. Leela works herself to the brink of exhaustion.
When one of the doctors is shot outside the hospital, the ER is put into lock down; a patient learns he is unable to receive a transplant due to his vaccination status; Devon and Leela try to juggle the new dynamics of their relationship.
A young boy comes into the hospital with a rare disease which leaves his bones incredibly fragile; with his clinical trial officially being declared a success, Devon has some huge decisions to make about the future of his career.
Conrad contemplates his future; Devon is presented with an amazing career opportunity.