A team comes together and searches to find out what's causing a rash of violent animal attacks.
Cast:James Wolk , Kristen Connolly , Nonso Anozie , Billy Burke , Alyssa Diaz , Josh Salatin , Nora Arnezeder , Gracie Dzienny , Athena Karkanis , Ken Olin , Jason Cermak , Jesse Muhoozi , Peter Outerbridge , Tom Butler , Hilary Jardine , Joanne Kelly , Michael Hogan , Madison Wolfe
Ten years after the animals were cured but at the cost of sterilizing the human population, a new threat rises in the form of "the hybrids," an army of unstoppable lab-made creatures focused on destroying mankind.
Jackson and Logan discover a link between the hybrid attacks that occur in Portland and New York; Mitch is interrogated by a woman claiming to be his daughter, Clementine; and a new development in Abraham's research into the sterility crisis endangers his family.
Jackson, Logan and Tessa's hunt for Abigail becomes dangerous when new hybrids appear. Abe and Dariela search for their son.
Abe and Dariela ponder over making a deal that will betray their friends. Abigail's game of cat and mouse continues. Clementine's past catches up to her.
While Jamie's under arrest, she manages to manipulate Mitch and Logan into helping her hunt shepherds, members of a secretive group responsible for sterilizing humans.
Mitch rushes to save Clementine from international corporate leaders. Jackson discovers he has hidden abilities.
As the team launches a rescue mission for Issac, Jaime and Mitch hunt for a large snake creature. Abigail's master plan comes to light.
Abigail holds Jackson prisoner in order to extract information from him that is critical to her secret master plan, and the team faces a mid-air crisis when their plane experiences an electrical malfunction.
After Mitch's alter ego, Mr. Duncan, attacks the team's plane then flees, Jamie, Abe and Max set out to find him and help.
Logan tries to destroy the hybrid nests before they activate. Clem's pregnancy undergoes a surprising development. The team tries to perfect the cure using Abigail and the hybrids.
As the team is trapped inside the plane by toxic spores surrounding them, complications arise during the delivery of Clementine's baby.
After the team's plane suffers a catastrophic accident in the hybrid zone, Dariela and Tess set out on a rescue mission to save them.
The team races to stop the hybrids from breaching the barrier wall by shutting down the last beacon that draws them in.